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2,000 individuals, aged 50-80 who have received a lung-RADS category 3 or 4 result on a LDCT screening study and who are scheduled for follow-up diagnostic imaging study, biopsy, clinical consultation or surgical appointment at one of the participating hospitals.
Adult male and female patients, aged 50 to 80 years
Received a lung RADS category 3 or 4 finding on a LDCT screening exam (first or subsequent) and are referred to undergo further diagnostic procedures for the detection of lung cancer
Has undergone LD-CT screening exam within last 90 days and allows for blood sampling within this period
Subject may not have undergone any invasive diagnostic procedure in relation to the suspicious nodule
Able and willing to provide informed consent
Exclusion Criteria:
Prior history of diagnosed lung cancer
History of gastrointestinal, hematological, breast, thyroid, and genitourinary cancer within the past 10 years
Active infectious diseases, such blood borne viral diseases (e.g. AIDS, hepatitis)
Immunosuppressive medication
Deemed not able to participate in the study by the investigator