Study ID: HYBRID
HYBRID: Hybrid coronary revascularization trial
The purpose of the non-surgical study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease, i.e., blockages in more than one vessel supplying blood to the heart muscle.
The treatment options this study will compare are as follows:
- Hybrid Coronary Revascularization (HCR), which is a combination of surgery and catheter procedures to open clogged heart arteries
- Percutaneous Coronary Intervention (PCI), a catheter procedure to open clogged heart arteries.
There are no new or experimental procedures being tested in this study—both HCR and PCI are well-established procedures and are regularly performed in patients who have coronary artery disease. However, the FDA has not yet approved the drug-eluting stents used in PCI for all types of coronary artery disease. The researchers are studying the use of the drug-eluting stents in this trial in the same way they are used in clinical practice.
Must have been diagnosed with multi-vessel coronary artery disease involving the left main and/or left anterior descending arteries