Lee J. Guo, DO

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Practice Philosophy

"The good physician treats the disease; the great physician treats the patient who has the disease." – William Osler
It is my goal and privilege to provide my patients with the highest level of care.

Practice Name
  • Great Valley Medical Associates
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Locations and Appointments

Paoli Hospital, MOB II, Suite 120
255 West Lancaster Avenue
Paoli, PA 19301

Do you have questions or are you looking for help in choosing the right provider?

Call 1.866.CALL.MLH (1.866.225.5654), Monday through Friday between 8:00 am–6:00 pm ET, to speak with a member of our referral staff who can help find the doctor who is right for you.

About Lee J. Guo, DO

Dr. Lee J. Guo grew up in Boston, earned his undergraduate degree in biology from Boston College, and moved to Philadelphia to begin his medical education. After earning his medical degree from the Philadelphia College of Osteopathic Medicine he completed a one-year clinical research fellowship at Harvard Medical School’s Boston Children’s Hospital where he co-authored a book chapter “Disorders of the Eustachian Tube” and contributed to an original research project Minimally Invasive Functional Approach for Cholesteatoma Surgery. He returned to Philadelphia once more to complete his internship and residency in internal medicine at the Mercy Suburban Hospital in East Norriton.

Dr. Guo has been practicing internal medicine primary care since 2014 and has a keen interest in preventive health, patient education and men’s health. He is board-certified by the American Osteopathic Board of Internal Medicine. When not providing patient care, Dr. Guo enjoys spending time with his family, playing the piano, and enjoying the grandeur of the great outdoors.

  • Gender: Male
  • Language: English, Chinese, Mandarin, Cantonese
Specialties Accepting New Patients
Internal Medicine Board certified since 2014


Medical school
  • Philadelphia College of Osteopathic Medicine
  • Mercy Suburban Hospital
  • Mercy Suburban Hospital
  • Children’s Hospital of Boston

*Members of the Main Line Health medical staff are affiliated with Bryn Mawr Hospital, Lankenau Medical Center, Paoli Hospital and Riddle Hospital. Membership on the medical staff of any of our hospitals does not constitute an employment or agency relationship.

Awards & Memberships

Current Membership & Activities
  • American Medical Association
  • American Osteopathic Association
  • Pennsylvania Osteopathic Medical Association
  • American College of Physicians