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Cancer studies and population health research advanced at LIMR with new appointments

August 2, 2019 Research News

Lankenau Institute for Medical Research (LIMR), part of Main Line Health, recently expanded its expertise in cancer studies and population health research with the addition of two new investigators.

Marie Webster, PhD

Dr. Webster is a cancer researcher who is working to elucidate how cancer cells change their character to gain the ability to metastasize and create therapeutic resistance. She received her PhD in pharmacology and molecular sciences from the Johns Hopkins University School of Medicine. Prior to her appointment at LIMR, she conducted postdoctoral research at the Wistar Institute in Philadelphia, after which she was appointed a staff scientist, focusing on understanding how the tissue microenvironment of a tumor changes to enable metastatic development and treatment resistance.

“With tremendous enthusiasm we welcome Dr. Webster to LIMR’s resident faculty,” said George Prendergast, PhD, president and CEO of LIMR. “Her expertise in gene expression mechanisms that drive changes in the tumor microenvironment and enable metastatic progression represents a leading edge of research in the field. I am delighted by the prospects of the contributions of her work to our program in cancer research, which is sure to have a great impact on LIMR and its mission to advance human health.”

Since 2004, Dr. Webster has been a lead author and co-author of 19 original research reports published in leading peer-reviewed scientific journals, including Nature, Cancer Discovery and Clinical Cancer Research. She is a member of the American Association for Cancer Research and the Association for Women in Science.

In advancing her important work, Dr. Webster was awarded a prestigious K99/R00 career development award from the National Cancer Institute, the next phase of which will be pursued through her new appointment at LIMR.

Kyle McGregor, PhD

Dr. McGregor joined the Main Line Health Center for Population Health Research (CPHR) at LIMR. His interests include empirical research ethics, data analytics, and adolescent health and development. He is an expert in research methodology, focusing much of his efforts on the ethical use of unstructured data related to highly vulnerable populations.

Dr. McGregor completed his PhD on a National Center for Advancing Translational Sciences Award at Indiana University. As a PhD candidate he also completed a fellowship in clinical ethics at the Charles Warren Fairbanks Center for Medical Ethics. He conducted his postdoctoral training in medical informatics at Yale University as a National Library of Medicine postdoctoral fellow. After leaving Yale he completed a second postdoctoral fellowship in the SAFE Lab at Columbia University.

Prior to joining CPHR, he served as director of pediatric mental health ethics at NYU Langone Health, New York City, where he was an assistant professor of child and adolescent psychiatry and population health.

“Dr. McGregor brings to LIMR’s population health research team a unique perspective that combines data science, social work, adolescent health, and technology use and innovations in health care that can identify crucial needs within our community and propose potential solutions,” said Sharon Larson, PhD, executive director of CPHR. “We are thrilled to welcome him.”

Since 2014, Dr. McGregor has been a lead author and co-author of studies that have been published in leading peer-reviewed publications, including Pediatrics, Journal of the American Medical Informatics Association, Ethics & Human Research, and Social Science Computer Review. He is a member of the Society for Adolescent Health and Medicine and an ethics committee member for the American Medical Informatics Association.

About Main Line Health

Founded in 1985,Main Line Health is a not-for-profit health system serving portions of Philadelphia and its western suburbs. Main Line Health’s commitment—to deliver advanced medicine to treat and cure disease while also playing an important role in prevention and disease management as well as training physicians and other health care providers—reflects our intent to keep our community and ourselves well ahead. A team of more than 10,000 employees and 2,000 physicians care for patients throughout the Main Line Health system.

At Main Line Health’s core are four of the region’s most respected acute care hospitals—Lankenau Medical Center, Bryn Mawr Hospital, Paoli Hospital and Riddle Hospital—as well as one of the nation’s recognized facilities for rehabilitative medicine, Bryn Mawr Rehabilitation Hospital.

Main Line Health also includes Mirmont Treatment Center for drug and alcohol recovery; Main Line Health HomeCare & Hospice, which includes skilled home health care, hospice and home infusion services; Main Line Health Centers, primary and specialty care, lab and radiology, and other outpatient services located in Broomall, Collegeville, Concordville, Exton, King of Prussia and Newtown Square; Lankenau Institute for Medical Research, a biomedical research organization; and Main Line HealthCare,one of the region’s largest multispecialty physician networks.

Main Line Health is the recipient of numerous awards for quality care and service, including System Magnet® designation, the nation’s highest distinction for nursing excellence and the Mid-Atlantic Alliance for Performance Excellence (MAAPE) Excellence Award. Main Line Health is committed to creating an environment of diversity, respect and inclusion and has proudly embraced the American Hospital Association’s #123forEquity Pledge to Act to eliminate disparities in care. We are dedicated to advancing patient-centered care, education and research to help our community stay healthy.

About Lankenau Institute for Medical Research

Lankenau Institute for Medical Research (LIMR) is a nonprofit biomedical research institute located on the campus of Lankenau Medical Center and is part of Main Line Health. Founded in 1927, LIMR’s mission is to improve human health and well-being. Faculty and staff are devoted to advancing innovative new approaches to formidable medical challenges, including cancer, cardiovascular disease, gastrointestinal disorders and autoimmune diseases, such as diabetes and arthritis. LIMR’s principal investigators conduct basic, preclinical and translational research, using their findings to explore ways to improve disease detection, diagnosis, treatment and prevention. They are committed to extending the boundaries of human health through technology transfer and training of the next generation of scientists and physicians.

About Main Line Health Center for Population Health Research (CPHR) at Lankenau Institute for Medical Research

Founded in 2016, the Center for Population Health Research (CPHR) is a joint collaboration between Main Line Health and Thomas Jefferson University’s College of Population Health. CPHR’s mission is to advance the understanding of population health by being a research and educational partner to Main Line Health, informing and assessing initiatives to improve the health status and quality of life in the communities it serves. CPHR’s researchers identify effective models to improve population health, as well as build evidence on successful implementation strategies.