Types of Acute Myeloid Leukemia (AML)

AML is classified according to what the leukemia cells look like under the microscope. There are nine subtypes of AML. They are called M0 through M7, with two M4 subtypes. This system gives some sense of your prognosis, so you can talk with your doctor about it. Your outcome depends greatly upon test results, such as cytogenetic analysis.

  • M0 (Undifferentiated AML).  About 5 percent of people with AML have this subtype. The prognosis is worse than average.

  • M1 (Myeloblastic leukemia with minimal maturation).  About 15 percent of people with AML have this subtype. The prognosis is average.

  • M2 (Myeloblastic leukemia with maturation.  About 25 percent of people with AML have this subtype. The prognosis is better than for most other types of AML.

  • M3 (Promyelocytic leukemia).  About 10 percent of people with AML have this subtype. It has the best prognosis of all the AML subtypes.

  • M4 (Myelomonocytic leukemia).  About 20 percent of people with AML have this subtype. The prognosis is average.

  • M4eo (Myelomonocytic leukemia with eosinophilia).  About 5 percent of people with AML have this subtype. The prognosis is better than average.

  • M5 (Monocytic leukemia).  About 10 percent of people with AML have this subtype. The prognosis is average.

  • M6 (Erythroid leukemia).  About 5 percent of people with AML have this subtype. The prognosis is worse than average.

  • M7 (Megakaryoblastic leukemia).  About 5 percent of people with AML have this subtype. The prognosis is worse than average.


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