Valine

Other Name(s):

a-amino-isovaleric acid

Unsubstantiated Claims:

Please note that this section reports on claims that have NOT yet been substantiated through scientific studies.

Valine may help treat malnutrition associated with drug addiction.

Recommended Intake:

Amino acids (AAs) are available as individual AAs or in proprietary AA combinations, as well as part of multi-vitamin formulas, proteins and food supplements. The forms include tablets, fluids and powders. However, adequate protein in the diet should provide a sufficient source of all amino acids.

Valine supplements should be taken together with leucine and isoleucine.

There are no conditions that increase the requirements for valine.

Side Effects, Toxicity and Interactions:

The use of a single amino acid supplement may lead to a negative nitrogen balance, decreasing metabolic efficiency and increasing the workload in the kidneys. In children, taking single amino acid supplements may also harmfully affect growth parameters.

Always avoid taking individual amino acids in high dosage for prolonged periods.

Women who are pregnant or breast-feeding should not use valine supplements.

Individuals with maple syrup urine disease (MSUD), a rare inherited disorder, should also avoid supplemental use of valine.

Additional Information:

Click here for a list of reputable Web sites with general information on nutrition.

References:

  1. Weast RC, Astle MJ, Beyer WH, eds. Handbook of Chemistry and Physics. 65th ed. Boca Raton, FL: CRC Press, Inc.; 1984.

  2. Lide DR, Frederikse HPR, eds. Handbook of Chemistry and Physics. 75th ed. Boca Raton, FL: CRC Press, Inc.; 1994.

  3. Murray RK, Granner DK, Mayes PA, Rodwell VW. Harper's Biochemistry. 25th ed. Stamford, CT: Appleton & Lange; 2000.

  4. Meisenberg G, Simmons WH. Principles of Medical Biochemistry. Mosby Pub. Co.; 1998.

  5. Styer L. Biochemistry. 4th ed. W.H. Freeman & Co.; 1995.

  6. Montgomery R, Conway TW, Spector AA, Chappell D. Biochemistry: A Case-Oriented Approach. 6th ed. Mosby Pub. Co.; 1996.

  7. Behrman RE, Kliegman RM, Nelson EE, Vaughan VC, eds. Nelson Textbook of Pediatrics. 14th ed. Philadelphia, PA: W.B. Saunders Co.; 1992.

  8. Nelson WE, Behrman RE, Kliegman RM, Arvin AM, eds. Nelson Textbook of Pediatrics. 15th ed. Philadelphia: W.B. Saunders Company; 1996.

Connect with MLH

New Appointments
1.866.CALL.MLH

 Well Ahead Newsletter


Connect With MLH

Copyright 2014 Main Line Health

Printed from: www.mainlinehealth.org/stw/Page.asp

The information provided in this Web site is for informational purposes only. It is not a substitute for medical advice. All medical information presented should be discussed with your healthcare professional. See additional Terms of Use at www.mainlinehealth.org/terms. For more information, call 1.866.CALL.MLH.