Center for Clinical Cancer Research

The Center for Clinical Cancer Research (CCCR) promotes and supports all cancer research across Main Line Health (MLH). The CCCR, led by Director Paul Gilman, MD, Chief, Division of Hematology/Oncology, LMC, oversees both NCI and non-NCI sponsored clinical and non-clinical trials within LIMR. These include novel trials of experimental therapeutics in oncology, drug development in partnership with pharmaceutical companies, and investigator-initiated trials, which relate to methods, tests and drugs developed here at LIMR. George Prendergast, PhD, Professor, President and CEO of LIMR, is a co-director with Dr. Gilman of the LIMR Program in Cancer Research. The synergy between LIMR’s laboratory programs and the clinical research activities serves as a translational conduit for the movement of laboratory findings into clinical investigations.

Dr. Gilman is also the principal investigator of the Main Line Health Community Clinical Oncology Program (CCOP), a cancer clinical trials program sponsored by the National Cancer Institute (NCI). The MLH CCOP, one of only 47 in the United States, consists of cancer treatment, control, and prevention trials. The many advantages of the NCI-sponsored consortium between Lankenau Medical Center, Bryn Mawr Hospital, and Paoli Hospital to the MLH community include having access to state-of-the-art clinical trials and new cancer treatments before they become available to the general public, and allowing patients to be more active in their healthcare. Community education is a critical component of the CCOP, which aims to improve patient awareness, services, and clinical outcomes to the nearly one million people residing in Main Line Health’s service area. For more information about cancer clinical trials and the NCI CCOP, please download our brochure.

Community Clinical Oncology Program Trials (CCOP) (pdf)
Other Cancer Clinical Trials and Research Studies (pdf)

Services provided by the CCCR in conjunction with the Clinical Research Center (CRC)

• Feasibility review
• Funding and budgeting review
• Communication with sponsor
• Guidance for regulatory/IRB submission
• Organizing initial site visits and ongoing audit visits
• Data management guidance
• Research coordinators
• Marketing
• Contract review

Additional services available for investigator-initiated trials

• Protocol development
• Statistical design and data analysis
• Assistance with informed consent form preparation
• Case report form design
• Editorial assistance for manuscript preparation

Clinical Trial Initiation Forms

CCCR Overview
Investigator Study Submission Form
Projected Costs Checklist

CCCR Staff

Paul Gilman, MD – CCCR Director; CCOP Principal Investigator; Co-Director, LIMR Program in Cancer Research
George Prendergast, PhD – Co-Director, LIMR Program in Cancer Research
Gerald Messerschmidt, MD – Director, Clinical Research Center
Diana Blade, MPH, CCRP - CCOP Administrator

For more information or questions regarding the Center for Clinical Cancer Research or the Community Clinical Oncology Program, please contact Diana Blade, 484-476-2649.