Cardiovascular Disease Research

Cardiovascular disease is the most prominent killer in the U.S. after cancer. LIMR researchers focus on developing new drugs and devices to correct heart beat disorders, treat and prevent heart attacks and strokes, and avert heart failure. Some work is also dedicated to monitoring and analyzing our clinical progress in improving patient outcomes. In our basic research component, we study underlying causes of high blood pressure (hypertension) and a unique class of stem cells studied at LIMR that may be useful for cardiac regeneration.

LIMR Faculty Involved in Cardiovascular Research

Robert Cox, PhD – hypertension, calcium channels, potassium channel function, atherosclerosis

Donglin Guo, MD, PhD - heart failure, arrhythmias, electrophysiology, ion channels, patch clamp

Peter R. Kowey, MD – arrhythmia, electrophysiology, atrial fibrillation, sudden cardiac death, antiarrhythmic drugs, cardiac pharmacology, anticoagulants, cardiac toxicity of non-cardiac drugs

Lisa D. Laury-Kleintop, PhD – atherosclerosis, negative tissue remodeling, statins, cardiomyopathy, diabetes

Melvin Reichman, PhD (LIMR Chemical Genomics Center) - drug discovery, high throughput screening, molecular pharmacology, chemical diversity

Gan-Xin Yan, MD, PhD - rapid and irregular heartbeat, myocardial infarction, enlarged and weakened heart, abnormal heart rhythms

Li Zhang, MD – inherited arrhythmias, cardiovascular outcomes