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Laura Mandik-Nayak, PhD

Laura Mandik-Nayak, PhD

Associate Professor

Rheumatoid arthritis (RA) results from the immune system's attack of the joints, triggering inflammation and chronic pain, eventually leading to progressive and debilitating destruction of cartilage and bone.

Current treatment is not effective at controlling disease progression as it relies on the reduction of inflammation by focusing on the end stage of the disease. Dr. Laura Mandik-Nayak has taken a different approach by targeting the early stage of RA. Her lab focuses on the triggering mechanisms by which the immune system becomes activated to induce inflammation in the joints. Dr. Mandik-Nayak’s data demonstrated that removal of an enzyme elevated in RA interferes with arthritis development, suggesting a role in the disease process. More...

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