Li Zhang, MD

Photo of Li Zhang


Phone: 484.476.2694

Office: R129-A

Department: Faculty

Association: Resident Faculty

Clinical Department: Cardiology

Other Appointment:Director, Cardiovascular Outcomes Research, Main Line Health


1977-82 Doctor of Medicine, Xi’an Medical University, Xi’an, China

Current Appointments:

2008 to Present: Director, Cardiovascular Outcomes Research, Main Line Health Heart Center, Lankenau Medical Center

2010 to Present: Associate Professor, Lankenau Institute for Medical Research

Research Interests:

Research Summary

Dr. Li Zhang, a clinical research scientist and Associate Professor of Jefferson Medical College, is specialized in investigating inherited arrhythmias associated with increased risks of sudden death in young otherwise healthy individuals. Li is a principal investigator (PI) of an ongoing project entitled “sudden death prevention-identifying the ECG markers in the early stage of ARVD awarded by American Heart Association Scientist Development Grant (2007-2012)” and a PI for a new study entitled “Lack of Adaptive Left Ventricular Hypertrophy in Athletes with Arrhythmogenic Right Ventricular Dysplasia-Is it a Disease Indicator? awarded by Sharpe-Strumia Research Foundation (2011-2012). She is also a co-investigator in the mutation functional expression studies of ARVD and LQTS sponsored by AHA and NIH (PI, Zhengfeng Zhou, Univ. of Oregon, 2008-2012), respectively.  Dr. Zhang’s primary research goal is to improve the early diagnosis of lethal heart rhythm disorder for prompt medical intervention and sudden death prevention. She is an author/co-author of more than 140 research publications in peer reviewed cardiology journals.  She is also a major contributor in establishing LQTS, ARVD and left ventricular noncompaction registry studies in China.

Dr. Zhang's Google Scholar page

2016 Select Publications 

Does Anemia Cause QT Prolongation in Patients with Hematologic Disorders? Fei YD, Li YG, Surkis W, Zhang L. Chinese Med J. 2016 (Accepted)

2015 Select Publications

Common Genotypes of Long QT Syndrome in China and the Role of ECG Prediction. Gao YF, Liu WL, Li CL, Qiu XL, Qin XG, Guo BJ, Liu XQ, Li JF, Yuan Y, Li XM, Liang L, LI L, Hong K, Pu JL, Liu JQ; Wang Q, Zhang L, Hu DY. Cardiology.  2016;133:73–78.

Right Ventricular Outflow Tract Tachycardia with Structural Abnormalities of the Right Ventricle and Left Ventricular Diverticulum. Martini B, Trevisi N, Martiniaf N, Zhang L. Case Reports in Cardiology  2015. Article ID 708687,

2014 Select Publications

Is the phenotype-genotype relationship necessary to understand cardiomyopathies? Fontaine GH, Zhang L. Corc Cardopvasc Genet. 7(4):405-6, 2014.

Identification of Kv11.1 Isoform Switch as a Novel Pathogenic Mechanism of Long QT Syndrome. Gong Q, Stump M, Deng V,  Zhang L, Zhou Z. Circ Cardiovasc Genet. 7:482-490, 2014.

Hypertrophic Cardiomyopathy: Can the Noninvasive Diagnostic Testing Identify High Risk Patients? Zhang L, Mmagu O, Liu LW, Li DY, Fan YX, Baranchuk A, Kowey PR. World J Cardiol. 6(8):764-70, 2014.

2013 Select Publications

The Phenotype Characteristics of Type-13 Long QT Syndrome. Wang F, Liu JQ, Hong L, Liang L, Graff C, Yang YZ, Christiansen M, Olesen SP, Zhang L, Kanters JK. Heart Rhythm. 10(10):1500-6, 2013.

Mega-Epsilon Waves on 12-Lead ECG — Just Another Case of Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy? Khaji A, Zhang L, Kowey PR, Martinez-Lage M, Kocovic D.  J Electrocardiol. 46(6):524-7, 2013.

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