Li Zhang, MD

Photo of Li Zhang


Phone: 484.476.2694

Office: R129-A

Department: Faculty

Association: Resident Faculty

Clinical Department: Cardiology

Other Appointment:Director, Cardiovascular Outcomes Research, Main Line Health


1977-82 Doctor of Medicine, Xi’an Medical University, Xi’an, China

Current Appointments:

2008 to Present: Director, Cardiovascular Outcomes Research, Main Line Health Heart Center, Lankenau Medical Center

2010 to Present: Associate Professor, Lankenau Institute for Medical Research

Research Interests:

Research Summary

Dr. Li Zhang, a clinical research scientist and Associate Professor of Jefferson Medical College, is specialized in investigating inherited arrhythmias associated with increased risks of sudden death in young otherwise healthy individuals. Li is a principal investigator (PI) of an ongoing project entitled “sudden death prevention-identifying the ECG markers in the early stage of ARVD awarded by American Heart Association Scientist Development Grant (2007-2012)” and a PI for a new study entitled “Lack of Adaptive Left Ventricular Hypertrophy in Athletes with Arrhythmogenic Right Ventricular Dysplasia-Is it a Disease Indicator? awarded by Sharpe-Strumia Research Foundation (2011-2012). She is also a co-investigator in the mutation functional expression studies of ARVD and LQTS sponsored by AHA and NIH (PI, Zhengfeng Zhou, Univ. of Oregon, 2008-2012), respectively.  Dr. Zhang’s primary research goal is to improve the early diagnosis of lethal heart rhythm disorder for prompt medical intervention and sudden death prevention. She is an author/co-author of more than 140 research publications in peer reviewed cardiology journals.  She is also a major contributor in establishing LQTS, ARVD and left ventricular noncompaction registry studies in China.

Dr. Zhang's Google Scholar page

Selected Publications

  1. Khaji A, Zhang L, Kowey PR, Martinez-Lage M, Kocovic D. Mega-Epsilon Waves on 12-Lead ECG— Just Another Case Of Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy? J Electrocardiol. 46(6):524-7, 2013.

  2. Wang F, Liu JQ, Hong L, Liang L, Graff C, Yang YZ, Christiansen M, Olesen SP, Zhang L, Kanters JK. The Phenotype Characteristics of Type-13 Long QT Syndrome. Heart Rhythm. 10(10):1500-6, 2013.

  3. Zhang L, Mmagu O, Liu LW, Li DY, Fan YX, Baranchuk A, Kowey PR. Hypertrophic Cardiomyopathy: Can the Noninvasive Diagnostic Testing Identify High Risk Patients? World J Cardiol, 6(8):764-70, 2014.

  4. Gong Q, Stump M, Deng V,  Zhang L, Zhou Z. Identification of Kv11.1 Isoform Switch as a Novel Pathogenic Mechanism of Long QT Syndrome. Circ Cardiovasc Genet. 7:482-490, 2014.

  5. Fontaine GH, Zhang L. Is the phenotype-genotype relationship necessary to understand cardiomyopathies? Corc Cardopvasc Genet 7(4):405-6, 2014.

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